Sheena Queen of the Jungle first appeared in Jumbo Comic #1 way back in 1939 -- she's a true pioneer. Very popular with soldier boys overseas in WWII, Fiction House decided to present her with her own title book three years later. In the first story of this issue she tries to stop a mad German scientist who is trying to develop a giant gorilla with special chemical injections. He is bent on "world conquest". Interestingly, the story is set in the year of 1916 (even though WWII is currently underway). The mad man charges at Sheena, she drops her knife, and he throws her down and starts strangling her. She is helpless to resist, and Bob (her mate) was knocked out a few moments earlier. She would have been strangled to death if Bob had not revived and rushed to save her. An exceptional tale because only rarely is she overpowered in one-on-one hand-to-hand combat, but that is the case here. Second story shows her chained on the splash page.
Source: Comicsworld