I really like it when Poison Ivy and Supergirl encounter each other. The DCAU episode "Girl's Night Out" is a great example of this. In it, Poison Ivy throws vine seeds at Supergirl, which then grow to entangle her.
In my drawing, Poison Ivy has introduced a new invention: Kryptonite pollen. The beautiful but deadly flowers keep Supergirl weakened, while Ivy sensually strokes Supergirl.