Gotham City Sirens #05-06

Catwoman (Selina Kyle), Poison Ivy (Pamela Lillian Isley) and Harley Quinn (Harleen Quinzel) set out to fight the Joker when they run into Gagsworth A. Gagsworthy, the Joker's original sidekick. Before confronting Harley Quinn he traps Catwoman, and then tries to incapacitate Poison Ivy with itching powder and 'Joker Venom'. After those fails, he uses 'pretty little bubbles'.
Source: Digital copy of comic