This, along with the scene from Ruse #22, is considered one of the top chloroform scenes ever made.
Emma Bishop, lead character of Crossgen's Ruse, is putting makeup on in her bedroom. An invisible figure sneaks into the room, holding a red cloth. The invisible man attempts to chloroform Emma. The panel on page #3 is a very well drawn scene.
Emma struggles while the guy tells her it'll just hurt for a moment.
Emma actually fights the guy off eventually, so she doesn't fully pass out. The struggles make the scene worth it however.